Author

F. M. Bashore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:rat· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. D. Axtman· 2 shared S. Howell· 2 shared A. Michaud· 1 shared A. N. Bullock· 1 shared B. A. Bunnell· 1 shared C. H. Rinderle· 1 shared C. I. Wells· 1 shared D. Drewry· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

A. D. Axtman

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Author profile →

2 papers

Recent·Most cited

Development of SYK NanoBRET Cellular Target Engagement Assays for Gain-of-Function Variants

J. L. Capener, J. D. Vasta, V. L. Katis, A. Michaud, M. T. Beck, S. C. D. Daglish, S. Cohen-Kedar, E. Shaham Barda, S. Howell, I. Dotan, M. B. Robers, A. D. Axtman, F. M. Bashore

The paper develops a NanoBRET assay to study SYK gain-of-function variants in live cells and demonstrates inhibitor efficacy against these variants.

bioRxiv · Jun 12, 2024Cell Biology

Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2

F. M. Bashore, S. M. Min, X. Chen, S. Howell, C. H. Rinderle, G. Morel, J. A. Silvaroli, C. I. Wells, B. A. Bunnell, D. Drewry, N. S. Pabla, S. K. Ultanir, A. N. Bullock, A. D. Axtman

The paper identifies and characterizes a chemical probe for CDKL2, demonstrating its selectivity and biological impact in neurons and cancer cells.

bioRxiv · May 12, 2024Cell Biology