Author

I. Dotan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:metagenomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. M. Rabinowitz· 3 shared A. Barzel· 2 shared A. D. Nahmad· 2 shared A. Levy-Barda· 2 shared H. Abu-Taha· 2 shared K. Kaboub· 2 shared M. Horovitz-Fried· 2 shared N. Wasserberg· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

K. M. Rabinowitz

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Discordant effects of ex-vivo JAK inhibition on inflammatory responses in colonic compared to ileal mucosa

K. Kaboub, H. Abu-Taha, J. Arrouasse, E. Shaham-Barda, N. Wasserberg, L. Hayman-Manzur, A. Friedenberg, A. Levy-Barda, I. Goren, H. Yanai, Z. Levi, H. Banai-Eran, I. Avni-Biron, J. E. Ollech, S. Cohen-Kedar, , K. M. Rabinowitz

This study examines how JAK inhibition affects inflammatory responses differently in colonic versus ileal mucosa from IBD patients and controls, finding site-specific effects and gene expression changes.

bioRxiv · Jan 18, 2024 · PreprintImmunology

Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis

S. Cohen-Kedar, E. Shaham Barda, K. M. Rabinowitz, D. Keizer, H. Abu-Taha, S. Schwartz, K. Kaboub, L. Baram, E. Sadot, I. White, N. Wasserberg, M. Wolff-Bar, A. Levy-Barda, I. Dotan

This study shows human intestinal epithelial cells internalize fungal particles via LC3-associated phagocytosis, contributing to mucosal tolerance.

bioRxiv · Dec 14, 2022Immunology

In vivo engineered B cells retain memory and secrete high titers of anti-HIV antibodies in mice

A. D. Nahmad, C. R. Lazzarotto, N. Zelikson, T. Kustin, M. Tenuta, D. Huang, I. Reuveni, M. Horovitz-Fried, I. Dotan, R. Rosin-Arbesfeld, D. Nemazee, J. E. Voss, A. Stern, S. Q. Tsai, A. Barzel

bioRxiv · Apr 8, 2021Immunology

B cells engineered to express an anti-HIV antibody allow memory retention, class switch recombination and clonal selection in mice

A. D. Nahmad, Y. Raviv, M. Horovitz-Fried, I. Sofer, T. Akriv, D. Nataf, I. Dotan, D. Burstein, Y. Wine, I. Benhar, A. Barzel

This study shows engineered B cells expressing anti-HIV antibodies can persist in mice, undergo class switch recombination, and show clonal selection after immunization.

bioRxiv · Feb 28, 2020Immunology

Prolonged Antibiotic Treatment Generates a Fluoroquinolone Resistant Gut Microbiome and Collateral Multi-Drug Resistance

V. Dubinsky, L. Reshef, N. Bar, K. Rabinowitz, L. Godny, H. Tulchinsky, U. Gophna, I. Dotan

This study shows that prolonged antibiotic treatment leads to widespread antibiotic resistance and collateral multi-drug resistance in the gut microbiome, with only modest bacterial density reduction.

bioRxiv · Nov 9, 2018Microbiology

Gut microbiota density influences host physiology and is shaped by host and microbial factors

E. J. Contijoch, G. J. Britton, C. Yang, I. Mogno, Z. Li, R. Ng, S. R. Llewellyn, S. Hira, C. Johnson, K. M. Rabinowitz, R. Barkan, I. Dotan, R. P. Hirten, S.-C. Fu, Y. Luo, , C

The paper examines factors influencing gut microbiota density across mammals, disease states, and interventions, finding host and microbial factors shape density and impact health.

bioRxiv · Jul 12, 2018Microbiology