Cell BiologybioRxivPreprint
IL-22 promotes acute kidney injury through activation of the DNA damage response and cell death in proximal tubule cells
DOI 10.1101/2023.06.08.544134
Author
N. S. Pabla
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2020-2023 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
H. W. Ong, Y. Liang, W. Richardson…·A. D. Axtman
The paper develops a potent and selective CDKL5/GSK3 chemical probe and demonstrates its neuroprotective effects in human motor neurons under ER stress.
DOI 10.1101/2023.02.09.527935 - BiochemistrybioRxiv
Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury
A. Rauckhorst, G. V. Martinez, G. M. Andrade…·D. Zepeda-Orozco
The paper shows that reducing mitochondrial pyruvate carrier activity in kidney tubular cells protects against acute kidney injury by enhancing redox defenses and survival.
DOI 10.1016/j.molmet.2023.101849 - Pharmacology & ToxicologybioRxivPreprint
Nephrotoxicity of the BRAF-kinase inhibitor Vemurafenib isdriven by off-target Ferrochelatase inhibition
Y. Bai, J. Y. Kim, L. A. Jayne…·N. S. Pabla
This study identifies off-target ferrochelatase inhibition as a mechanism of vemurafenib-induced nephrotoxicity in renal tubular epithelial cells.
- Cell BiologybioRxiv
SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in kidney epithelial cells
J. Y. Kim, Y. Bai, L. A. Jayne…·N. S. Pabla
The paper identifies VGF as a stress-responsive protective gene in kidney epithelial cells, showing that SOX9 drives its transcription during injury.
DOI 10.1074/jbc.ra120.015110