Canagliflozin Extends Lifespan in Genetically Heterogeneous Male But Not Female Mice
R. A. Miller, D. E. Harrison, D. B. Allison, M. Bogue, V. Diaz, E. Fernandez, A. Galecki, W. T. Garvey, N. Kumar, M. A. Javors, W. C. Ladies, F. Macchiarini, J. Nelson, P. Reifsnyder, N. A. Rosenthal, , R. Strong
This study shows canagliflozin extends lifespan in male but not female mice, likely by reducing peak glucose levels, similar to acarbose.
bioRxiv · May 23, 2020 · PreprintPathology