Author

D. B. Allison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. Liu· 4 shared C. Li· 3 shared F. Mao· 3 shared Q. ZHANG· 3 shared X. Liu· 3 shared X. Wang· 3 shared Y. Kong· 3 shared Y. Zhang· 3 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

J. Liu

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Dysregulation of mitochondrial function by PLK1-mediated PDHA1 phosphorylation promotes Cr(VI)-associated lung cancer progression

Q. ZHANG, Z. Li, X. Rao, D. B. Allison, Q. Qiao, Z. Zhang, Y. Kong, Y. Zhang, R. Wang, J. Liu, X. Wang, C. Li, F. Mao, W. Katz, Q. Shao, , X. Liu

This study shows that PLK1-mediated PDHA1 phosphorylation impairs mitochondrial function and promotes Cr(VI)-induced lung cancer progression by disrupting energy metabolism and apoptosis.

bioRxiv · Feb 16, 2024 · PreprintCancer Biology

Single-cell analysis characterizes PLK1 as a catalyst of an immunosuppressive tumor microenvironment in LUAD

Y. Kong, C. Li, J. Liu, M. Zhang, D. B. Allison, F. Hassan, D. He, X. Wang, F. Mao, Q. Zhang, Y. Zhang, Z. Li, S. Wu, C. Wang, X. Liu

This study identifies PLK1 as a driver of an immunosuppressive tumor microenvironment in LUAD through single-cell RNA-seq and genetic models.

bioRxiv · Aug 2, 2023 · PreprintCancer Biology

Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling

C. Li, D. B. Allison, D. He, F. Mao, X. Wang, P. Rychahou, I. A. Imam, Y. Kong, Q. Zhang, Y. Zhang, J. Liu, R. Wang, X. Rao, S. Wu, Q. Shao, , X. Liu

This study shows that PLK1 phosphorylates AHR in LUAD, promoting metastasis through DIO2-TH signaling.

bioRxiv · Jul 31, 2023Cancer Biology

Impact of aging on the immunological and microbial landscape of the lung during non-tuberculous mycobacterial infection

I. R. Cinco, N. S. Rhoades, E. G. Napier, M. Davies, D. B. Allison, S. G. Kohama, L. E. Bermudez, K. Winthrop, C. Fuss, E. R. Spindel, I. Messaoudi

This study investigates how aging affects the immune and microbial environment in the lungs during NTM infection using a rhesus macaque model.

bioRxiv · Feb 11, 2023 · PreprintImmunology

Mass Spectrometry Imaging of N-Glycans Reveals Racial Discrepancies in Low Grade Prostate Tumors

L. R. Conroy, L. E. Young, A. E. Stanback, G. L. Austin, J. Liu, J. Liu, D. B. Allison, R. C. Sun

This study uses mass spectrometry imaging to identify racial differences in N-glycan profiles of low-grade prostate tumors and links these differences to survival outcomes.

bioRxiv · Aug 20, 2020 · PreprintCancer Biology

Canagliflozin Extends Lifespan in Genetically Heterogeneous Male But Not Female Mice

R. A. Miller, D. E. Harrison, D. B. Allison, M. Bogue, V. Diaz, E. Fernandez, A. Galecki, W. T. Garvey, N. Kumar, M. A. Javors, W. C. Ladies, F. Macchiarini, J. Nelson, P. Reifsnyder, N. A. Rosenthal, , R. Strong

This study shows canagliflozin extends lifespan in male but not female mice, likely by reducing peak glucose levels, similar to acarbose.

bioRxiv · May 23, 2020 · PreprintPathology