Author

F. Muyas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

I. Cortes-Ciriano· 4 shared A. Bhutkar· 1 shared A. C. De Luca· 1 shared A. Giess· 1 shared A. Jin· 1 shared A. M. Cruz· 1 shared A. M. Flanagan· 1 shared A. M. Jaeger· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersCancer Biology

I. Cortes-Ciriano

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Author profile →

4 papers

Recent·Most cited

Mechanisms underpinning osteosarcoma genome complexity and evolution

J. Espejo Valle-Inclan, S. De Noon, K. Trevers, H. Elrick, M. Tanguy, T. Butters, F. Muyas, F. Amary, R. Tirabosco, A. Giess, A. Sosinky, G. Elgar, A. M. Flanagan, I. Cortes-Ciriano

This study identifies chromothripsis and a novel LTA chromothripsis mechanism driving genome complexity and evolution in osteosarcoma, with prognostic implications for high-grade tumors.

bioRxiv · Dec 29, 2023 · PreprintCancer Biology

Profilin 1 deficiency drives mitotic defects and impairs genome stability

F. Scotto di Carlo, S. Russo, F. Muyas, M. Mangini, L. Pazzaglia, F. Biamonte, A. C. De Luca, K. Scotlandi, I. Cortes-Ciriano, F. Gianfrancesco

This study shows that Profilin 1 deficiency causes mitotic defects and genome instability in cancer cells.

bioRxiv · Feb 1, 2022Cell Biology

The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients

F. Muyas, M. J. Gomez Rodriguez, I. Cortes-Ciriano, I. Flores

The paper identifies telomere fusions as a genomic signature of the ALT pathway in cancer, detectable in blood for early cancer detection.

bioRxiv · Jan 25, 2022Cancer Biology

Mismatch repair deficiency is not sufficient to increase tumor immunogenicity

P. M. K. Westcott, F. Muyas, O. Smith, H. Hauck, N. J. Sacks, Z. A. Ely, A. M. Jaeger, W. M. Rideout, A. Bhutkar, D. Zhang, M. C. Beytagh, D. A. Canner, R. T. Bronson, S. Naranjo, A. Jin, , T. Jacks

This study shows that MMRd in mouse tumor models does not increase immunogenicity or ICB response, due to intratumoral heterogeneity.

bioRxiv · Aug 24, 2021 · PreprintCancer Biology