Cell BiologybioRxiv
The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans
C. Heissenberger, T. L. Krammer, J. A. Rollins…·M. Schosserer
This study identifies NSUN-1 as an enzyme that methylates rRNA at position C2982 in C. elegans, showing that its depletion affects healthspan, oogenesis, and cuticle integrity.
DOI 10.7554/elife.56205