Author

F. Pajonk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Deb· 1 shared A. G. Alvarado· 1 shared A. Ioannidis· 1 shared A. Pham· 1 shared D. Geschwind· 1 shared E. Vlashi· 1 shared H. I. Kornblum· 1 shared H. Kornblum· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. Deb

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Author profile →

3 papers

Recent·Most cited

NADPH oxidase promotes glioblastoma radiation resistance in a PTEN-dependent manner

K. Ludwig, J. Le Belle, S. D. D. Muthukrishnan, J. Sperry, M. Condro, E. Vlashi, F. Pajonk, H. Kornblum

This study shows that NADPH oxidase promotes glioblastoma radiation resistance through PTEN-dependent ROS production and Akt activation.

bioRxiv · Jun 16, 2022Cancer Biology

Radiation-reprogrammed glioma stem cells generate vascular-like cells to build a trophic niche driving tumor recurrence

S. D. Muthukrishnan, R. Kawaguchi, P. Nair, R. Prasad, Y. Qin, M. Johnson, N. Vanderveer-Harris, A. Pham, Q. Wang, M. C. Condro, A. G. Alvarado, R. Gau, M. G. Castro, P. R. Lowenstein, A. Deb, , H. I. Kornblum

The paper shows radiation induces vascular-like phenotypes in glioma stem cells, creating a trophic niche that promotes tumor recurrence, and identifies P300 inhibition as a potential therapeutic strategy.

bioRxiv · Jun 3, 2021 · PreprintCancer Biology

Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer

L. He, K. Bhat, S. Duhacheck-Muggy, A. Ioannidis, L. Zhang, N. T. Nguyen, N. A. Moatamed, F. Pajonk

This study shows that reducing TNFR2 signaling in mice increases breast cancer incidence and aggressiveness, suggesting TNFR2 agonists could help prevent breast cancer in high-risk populations.

bioRxiv · Mar 12, 2020Cancer Biology