Author

F. Seehusen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Kipar· 1 shared A. Kirby· 1 shared A. Owen· 1 shared B. D. Michael· 1 shared D. Neri· 1 shared E. Bentley· 1 shared E. I. Patterson· 1 shared E. Puca· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPathology

A. Kipar

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouse

F. Seehusen, J. J. Clark, P. Sharma, E. Bentley, A. Kirby, K. Subramaniam, S. Wunderlin Giuliani, G. Hughes, E. I. Patterson, B. D. Michael, A. Owen, J. A. Hiscox, J. P. Stewart, A. Kipar

This study investigates SARS-CoV-2 variant neuroinvasion in K18-hACE2 mice, finding CNS spread in all variants except Omicron, with microglial activation and immune cell apoptosis observed.

bioRxiv · Apr 16, 2021Pathology

Comparative evaluation of bolus and fractionated administration modalities for two antibody-cytokine fusions in immunocompetent tumor-bearing mice

E. Puca, R. De Luca, F. Seehusen, J. M. M. Rodriguez, D. Neri

This study compares bolus and fractionated administration of two antibody-cytokine fusions in mice, finding that fractionation reduces toxicity for one but increases efficacy for another.

bioRxiv · Nov 7, 2019Pharmacology & Toxicology