PathologybioRxiv
Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouse
F. Seehusen, J. J. Clark, P. Sharma…·A. Kipar
This study investigates SARS-CoV-2 variant neuroinvasion in K18-hACE2 mice, finding CNS spread in all variants except Omicron, with microglial activation and immune cell apoptosis observed.
DOI 10.3390/v14051020