ImmunologybioRxiv
An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors
R. Singh, V. Rossini, S. R. Stockdale…·S. Melgar
The paper shows that AIEC synergizes with NSAID to worsen colitis in IL10 -/- mice, which is blocked by NLRP3 and Caspase-8 inhibitors.
DOI 10.1080/19490976.2022.2163838