Cell BiologybioRxiv
The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in maintaining mitochondrial metabolic homeostasis
A. Joshi, J. Dai, J. Lee…·D. Picard
This study shows TRAP1 forms an OXPHOS-regulated tetramer and is essential for maintaining mitochondrial metabolic homeostasis by modulating OXPHOS and interacting with mitochondrial chaperones.
DOI 10.1186/s12915-020-0740-7