Conserved epigenetic regulatory logic infers genes governing cell identity
W. J. Shim, E. Sinniah, J. Xu, B. Vitrinel, M. Alexanian, G. Andreoletti, S. Shen, Y. Sun, B. Balderson, C. Boix, G. Peng, N. Jing, Y. Wang, M. Kellis, P. Tam, , N. Palpant
This study introduces a computational method to identify genetic regulators of cell identity using epigenetic data across diverse species and validates findings with CRISPR experiments.
bioRxiv · Oct 9, 2020Cell Biology