Author

G. Castellano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Lopez-Guillermo· 1 shared A. Queiros· 1 shared A. Rivas· 1 shared C. Fillat· 1 shared C. Lopez-Otin· 1 shared C. Oakes· 1 shared D. Medel· 1 shared E. Campo· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Lopez-Guillermo

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2 papers

Recent·Most cited

BioengineeringbioRxivJun 19, 2020

Transgene codon usage drives viral fitness and therapeutic efficacy in oncolytic adenoviruses

E. Nunez-Manchon, M. Farrera-Sal, G. Castellano…·C. Fillat

This study shows that transgene codon usage affects viral fitness and oncolytic efficacy in adenoviruses, with suboptimal codons enhancing sustained expression and therapeutic activity.

DOI 10.1093/narcan/zcab015

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivFeb 6, 2020

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

M. Duran-Ferrer, G. Clot, F. Nadeu…·J. I. Martin-Subero

This study analyzes DNA methylation in B-cell tumors to show its relation to proliferative history and clinical outcomes, introducing a new mitotic clock for prognosis.

DOI 10.1038/s43018-020-00131-2

humanDNA methylation

𝕏 PostBluesky