E. Campo

High-dimensional single-cell definition of CLL T cells identifies Galectin-9 as novel immunotherapy target

The paper defines CLL T cell subtypes and identifies Galectin-9 as a novel immunotherapy target through single-cell and multi-omics analyses.

An Atlas of Cells in the Human Tonsil

The paper creates a comprehensive cell atlas of the human tonsil using single-cell multi-omics data, identifying 121 cell types and uncovering regulatory mechanisms and disease-related changes.

RFcaller: a machine learning approach combined with read-level features to detect somatic mutations

RFcaller uses machine learning with read-level features to detect somatic mutations accurately and efficiently in tumor-normal paired samples.

SAMHD1 mutations in mantle cell lymphoma are recurrent and confer in vitro resistance to nucleoside analogues

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

This study analyzes DNA methylation in B-cell tumors to show its relation to proliferative history and clinical outcomes, introducing a new mitotic clock for prognosis.

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

The paper identifies aberrant chromatin activation as a common mechanism driving the malignant phenotype in multiple myeloma.