Cell BiologybioRxivPreprint
Targeting SerpinE1 reverses cellular features of Hutchinson-Gilford progeria syndrome
G. Catarinella, C. Nicoletti, A. Bracaglia…·L. Latella
This study identifies SerpinE1 as a therapeutic target for HGPS by showing its inhibition reverses key pathological features in patient-derived fibroblasts.
DOI 10.1101/2021.11.05.467259