Cell BiologybioRxivPreprint
Therapeutic targeting of SETD2-deficient cancer cells with the small-molecule compound RITA
K. A. Lopez, S. Sarkar, E. Seraia…·T. C. Humphrey
This paper identifies RITA as a compound that selectively kills SETD2-deficient cancer cells by inducing p53-mediated apoptosis and replication stress.
DOI 10.1101/2021.07.08.451582