Author

F. Buffa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. L. Harris· 1 shared A. Mcintyre· 1 shared A. Valli· 1 shared C. Cooper· 1 shared C. Toffanin· 1 shared D. C. I. Goberdhan· 1 shared D. Ebner· 1 shared D. Jones· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. L. Harris

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Author profile →

2 papers

Recent·Most cited

Therapeutic targeting of SETD2-deficient cancer cells with the small-molecule compound RITA

K. A. Lopez, S. Sarkar, E. Seraia, C. Toffanin, C. Cooper, M. Challoumas, F. A. Okonjo, G. D. D. Jones, F. Buffa, D. Ebner, T. C. Humphrey

This paper identifies RITA as a compound that selectively kills SETD2-deficient cancer cells by inducing p53-mediated apoptosis and replication stress.

bioRxiv · Jul 8, 2021 · PreprintCell Biology

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine-resistance in breast cancer

M. Morotti, E. Bridges, A. Valli, H. Choudhry, H. Sheldon, S. Wigfield, N. Gray, D. Jones, E. J. Teoh, W.-C. Cheng, S. Lord, S. Haider, A. Mcintyre, D. C. I. Goberdhan, F. Buffa, A. L. Harris

This study shows hypoxia shifts SNAT2 regulation from ER to HIF-1 in breast cancer, leading to endocrine resistance and poor outcomes.

bioRxiv · Aug 3, 2018Cancer Biology