Author

G. Firth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:imaging· 2 Organism:chicken / avian· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Baark· 2 shared H. E. Greenwood· 2 shared L. M. Smith· 2 shared M. Tanc· 2 shared R. S. Edwards· 2 shared T. H. Witney· 2 shared W. E. Tyrrell· 2 shared A. Falzone· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

F. Baark

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography

H. E. Greenwood, R. S. Edwards, W. E. Tyrrell, A. R. Barber, F. Baark, M. Tanc, E. Khalil, A. Falzone, N. P. Ward, J. M. DeBlasi, L. Torrente, D. R. Pearce, G. Firth, L. M. Smith, O. Vilhelmsson Timmermand, , T. H. Witney

This study uses PET imaging to assess NRF2 activation in NSCLC, showing [18F]FSPG as a marker of therapeutic resistance and a potential target for treatment.

bioRxiv · Dec 16, 2023Cancer Biology

The Chicken Chorioallantoic Membrane as a Low-Cost, High-Throughput Model for Cancer Imaging

L. M. Smith, H. E. Greenwood, W. E. Tyrrell, R. S. Edwards, V. de Santis, F. Baark, G. Firth, M. Tanc, S. Y. A. Terry, A. Herrmann, R. Southworth, T. H. Witney

This paper evaluates the chicken chorioallantoic membrane as a low-cost, high-throughput alternative to mouse models for cancer imaging using PET/CT.

bioRxiv · Jun 21, 2023Cancer Biology

Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy

M. L. Read, K. Brookes, L. Zha, S. Manivannan, J. Kim, M. Kocbiyik, A. Fletcher, C. M. Gorvin, G. Firth, G. O. Fruhwirth, J. P. Nicola, S. Jhiang, M. D. Ringel, M. J. Campbell, K. Sunassee, , C. J. McCabe

This study identifies an acidic dipeptide in NIS that mediates AP2 binding, showing chloroquine enhances NIS membrane retention and RAI uptake in thyroid cancer.

bioRxiv · May 22, 2023 · PreprintCancer Biology