Perfusion-Independent Tissue Hypoxia in Cardiac Hypertrophy in Mice Measured by 64Cu-CTS PET Imaging
F. Baark, A. Michaels, E. Waters, A. Rigby, J. Kim, Z. Yu, V. Pell, J. Clark, P. Blower, T. R. Eykyn, R. Southworth
This study shows that 64Cu-CTS PET detects hypoxia in hypertrophic mouse hearts independent of perfusion, linking it to structural changes and metabolic shifts.
bioRxiv · Apr 22, 2024 · PreprintBioengineering