Author

G. Frankel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Animal Behavior & Cognition· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:E. coli· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Assay:whole-genome sequencing· 2 Organism:C. elegans· 1

Frequent Co-Authors

W. W. Low· 4 shared K. Beis· 3 shared A. Clements· 2 shared C. Seddon· 2 shared F. Morecchiato· 2 shared G. M. Rossolini· 2 shared J. Sanchez-Garrido· 2 shared J. Wong· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersMicrobiology

W. W. Low

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Re-engineering of TNFα-NF-κB signalling dynamics in cancer cells using pathogenic E. coli effectors

Q. Zhong, F. Butera, G. Frankel, C. Bakal

This study uses bacterial effectors to manipulate NF-κB signalling in cancer cells, showing that combining Tir, NleE, and TNF can eliminate 95% of pancreatic cancer cells with minimal NF-κB activation.

bioRxiv · Mar 3, 2023 · PreprintCell Biology

The interaction of the F-like plasmid-encoded TraN isoforms with their cognate outer membrane receptors

G. Frankel, W. W. Low, C. Seddon, K. Beis

This study investigates how sequence differences in outer membrane receptors affect TraN-mediated conjugation efficiency and specificity in bacteria.

bioRxiv · Feb 9, 2023 · PreprintMicrobiology

Emergent regulation of ant foraging frequency through a computationally inexpensive forager movement rule

L. Baltiansky, G. Frankel, O. Feinerman

The paper shows that ant foraging frequency is regulated by a simple movement rule based on food load, without requiring explicit decision-making.

bioRxiv · Feb 15, 2022Animal Behavior & Cognition

Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae

S. David, J. Wong, J. Sanchez-Garrido, J. Kwong, W. W. Low, F. Morecchiato, T. Giani, G. M. Rossolini, S. Brett, A. Clements, K. Beis, D. Aanensen, G. Frankel

This study identifies and characterizes OmpK36 loop 3 insertions in Klebsiella pneumoniae, showing their role in carbapenem resistance and clonal spread across different geographic regions.

bioRxiv · Feb 7, 2022Microbiology

Recurrent emergence of carbapenem resistance in Klebsiella pneumoniae mediated by an inhibitory ompK36 mRNA secondary structure

J. L. C. Wong, S. David, J. Sanchez-Garrido, J. Z. Woo, W. W. Low, F. Morecchiato, T. Giani, G. M. Rossolini, S. J. Brett, A. Clements, D. M. Aanensen, S. Rouskin, G. Frankel

This study identifies a synonymous mutation in ompK36 that increases carbapenem resistance in Klebsiella pneumoniae by causing translational suppression.

bioRxiv · Jan 5, 2022Microbiology

OmpK36 and TraN facilitate conjugal transfer of the Klebsiella pneumoniae carbapenem resistance plasmid pKpQIL

W. W. Low, J. Wong, A. Pena, C. Seddon, T. Costa, K. Beis, G. Frankel

This study identifies OmpK36 and TraN as key factors for conjugative transfer of the K. pneumoniae plasmid pKpQIL, revealing a novel receptor mechanism for IncF plasmids.

bioRxiv · Jul 1, 2020 · PreprintMicrobiology