Author

T. Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Pena· 2 shared A. B. Silva· 1 shared A. F. Mourao· 1 shared A. Figueiredo· 1 shared A. Ilangovan· 1 shared A. Neto· 1 shared C. Franco· 1 shared C. Lopes· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

A. Pena

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The immune landscape of murine skeletal muscle regeneration and aging

N. S. Sousa, M. Bica, M. F. Bras, I. A. Antunes, I. A. Encarnacao, T. Costa, I. B. Martins, N. L. Barbosa-Morais, P. Sousa-Victor, J. Neves

This study analyzes the immune environment in aging skeletal muscle using single-cell RNA-sequencing, flow cytometry, and functional assays, revealing new immune cell types and functional heterogeneity.

bioRxiv · Nov 7, 2023Cell Biology

A non-genetic model of vascular shunts informs on the cellular mechanisms of formation and resolution of arteriovenous malformations

M. Ouarne, A. Pena, D. Ramalho, N. Conchinha, T. Costa, A. Figueiredo, M. Saraiva, Y. Carvalho, L. Misikova, P. Oh, C. Franco

This study identifies EC volume changes as the key mechanism for AV shunt formation and regression, using a non-genetic model in mice.

bioRxiv · Aug 21, 2023Cell Biology

Positive and negative control of helicase recruitment at a bacterial chromosome origin

C. Winterhalter, D. Stevens, S. Fenyk, S. Pelliciari, E. Marchand, N. B. Cronin, P. Soultanas, T. Costa, A. Ilangovan, H. Murray

This study identifies positive and negative mechanisms controlling helicase recruitment during bacterial chromosome replication initiation in Bacillus subtilis, with implications for drug development targeting DnaD.

bioRxiv · Aug 16, 2021 · PreprintMicrobiology

Direct tissue sensing reprograms TLR4+ Tfh-like cells inflammatory profile in the joints of rheumatoid arthritis patients

D. Amaral-Silva, R. C. Torrao, R. Torres, S. Falcao, M. J. Goncalves, M. P. Araujo, M. J. Martins, C. Lopes, A. Neto, J. Marona, T. Costa, W. Castelao, A. B. Silva, I. Silva, M. H. Lourenco, , H. Soares

The paper identifies TLR4+ Tfh-like cells in RA patients that switch from producing IL-21 to IL-17 upon joint exposure, contributing to tissue damage.

bioRxiv · Feb 19, 2021Immunology

OmpK36 and TraN facilitate conjugal transfer of the Klebsiella pneumoniae carbapenem resistance plasmid pKpQIL

W. W. Low, J. Wong, A. Pena, C. Seddon, T. Costa, K. Beis, G. Frankel

This study identifies OmpK36 and TraN as key factors for conjugative transfer of the K. pneumoniae plasmid pKpQIL, revealing a novel receptor mechanism for IncF plasmids.

bioRxiv · Jul 1, 2020 · PreprintMicrobiology