Author

G. L. Righetto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:plant (other)· 1

Frequent Co-Authors

L. Halabelian· 3 shared A. Seitova· 2 shared D. Barsyte-Lovejoy· 2 shared H. Zeng· 2 shared M. Szewczyk· 2 shared P. Loppnau· 2 shared V. Santhakumar· 2 shared Y. Li· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

L. Halabelian

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Author profile →

3 papers

Recent·Most cited

A resource to enable chemical biology and drug discovery of WDR Proteins

C. H. Arrowsmith, S. Ackloo, F. Li, M. Szewczyk, A. Seitova, P. Loppnau, H. Zeng, S. Ahmad, S. Beldar, A. Bolotokova, I. Chau, S. Dehghani-Tafti, A. Dong, P. Ghiabi, E. Gibson, , Arnautova

The paper develops a resource for discovering ligands for WDR proteins using experimental and computational methods, leading to the identification of drug-like ligands for 9 out of 20 targets.

bioRxiv · Mar 3, 2024Biochemistry

Probing the DCAF12 interactions with MAGEA3 and CCT5 C-terminal degrons

G. L. Righetto, Y. Yin, V. Vu, D. Duda, M. Szewczyk, H. Zeng, Y. Li, P. Loppnau, T. Mei, Y.-Y. Li, A. Seitova, J.-F. Brazeau, D. Barsyte-Lovejoy, V. Santhakumar, C. Chaudhry, L. Halabelian

This study characterizes DCAF12 interactions with MAGEA3 and CCT5 degrons using biophysical assays and cryo-EM, revealing key residues for degron recognition and informing PROTAC design.

bioRxiv · Aug 15, 2023 · PreprintBiochemistry

The C-terminal domains SnRK2-box and ABA-box have a role in sugarcane SnRK2s auto-activation and activity

G. L. Righetto, D. Sriranganadane, L. Halabelian, C. Gottschald Chiodi, J. Elkins, K. B. Massirer, O. Gileadi, M. Menossi, R. Counago

This study investigates the role of SnRK2-box and ABA-box domains in sugarcane SnRK2s auto-activation and activity, revealing distinct regulatory mechanisms compared to Arabidopsis.

bioRxiv · Mar 26, 2019Plant Biology