Author

D. Duda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Matsui· 1 shared A. Seitova· 1 shared C. Chaudhry· 1 shared C. Huang· 1 shared C. Liao· 1 shared D. Barsyte-Lovejoy· 1 shared D. Kuang· 1 shared G. L. Righetto· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Matsui

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3 papers

Recent·Most cited

Combined blockade of CXCR4 and PD-1 enhances intratumoral dendritic cell activation and immune responses against HCC

S. Morita, K. Shigeta, P. Lei, T. Kobayashi, H. Kikuchi, A. Matsui, P. Huang, M. Pittet, D. Duda

This study shows that blocking CXCR4 and PD-1 together improves dendritic cell activation and immune responses against HCC in mouse models.

bioRxiv · Nov 6, 2023 · PreprintCancer Biology

Probing the DCAF12 interactions with MAGEA3 and CCT5 C-terminal degrons

G. L. Righetto, Y. Yin, V. Vu, D. Duda, M. Szewczyk, H. Zeng, Y. Li, P. Loppnau, T. Mei, Y.-Y. Li, A. Seitova, J.-F. Brazeau, D. Barsyte-Lovejoy, V. Santhakumar, C. Chaudhry, L. Halabelian

This study characterizes DCAF12 interactions with MAGEA3 and CCT5 degrons using biophysical assays and cryo-EM, revealing key residues for degron recognition and informing PROTAC design.

bioRxiv · Aug 15, 2023 · PreprintBiochemistry

Distinct Single-cell Immune Ecosystems Distinguish True and De Novo HBV-related Hepatocellular Carcinoma Recurrences

S. Chen, C. Huang, G. Liao, H. Sun, Y. Xie, J. Wang, M. He, H. Hu, Z. Dai, X. Ren, X. Zeng, Q. Zeng, G. Zhang, C. Liao, W. Xie, , M. Kuang

This study identifies distinct immune ecosystems in true and de novo HBV-related HCC recurrences using single-cell and bulk RNA-sequencing, revealing differences in T cell phenotypes and immune interactions that may inform immunotherapy strategies.

bioRxiv · Jun 2, 2022Immunology