Author

G. Lentini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Beck· 1 shared A. Chandran· 1 shared A. Kumawat· 1 shared A. Matson· 1 shared A. P. Naren· 1 shared A. Schon· 1 shared A. Trancuccio· 1 shared A. Vrzalova· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Beck

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations.

A. Kumawat, E. Tavazzani, G. Lentini, A. Trancuccio, D. Kukavica, M. Denegri, S. G. Priori, C. Camilloni

This study investigates how ICA-105574, an HERG activator, shortens cardiac repolarization in severe LQT2 mutations through molecular mechanisms.

bioRxiv · Mar 13, 2024Biophysics

Camel urine limits proliferation and modifies cell morphology in human renal tumoral and non-tumoral cells

C. Iglesias Pastrana, M. N. Sgobba, F. J. Navas Gonzalez, J. V. Delgado Bermejo, I. F. Duarte, G. Lentini, T. Kamal Sayed Osman, L. Guerra, E. Ciani

This study investigates the antiproliferative and morphological effects of camel urine on human renal cells, finding significant effects only in tumoral cells.

bioRxiv · Sep 12, 2022 · PreprintCell Biology

Targeting the Pregnane X Receptor Using Microbial Metabolite Mimicry

Z. Dvorak, F. Felix Kopp, C. M. Costello, J. S. Kemp, H. Li, A. Vrzalova, M. Stepankova, I. Iveta Bartonkov, K. Poulikova, B. Vyhlidalova, L. U. Nordstroem, C. Karunaratne, H. Ranhotra, K. S. Mun, A. P. Naren, , R. B. Sartor

This paper develops FKK6, a non-cytotoxic PXR agonist derived from microbial metabolite mimicry, which reduces inflammation and validates the strategy for drug discovery.

bioRxiv · Jan 3, 2020Biochemistry