ImmunologybioRxivPreprint
Functional mRNA delivery to hematopoietic stem and progenitor cells in vivo.
D. Alvarez, G. Masse-Ranson, S. K. Sedimbi…·J. R. Mora
This study demonstrates in vivo delivery of functional mRNA to hematopoietic stem cells (HSC) using lipid nanoparticles, achieving transfection in ~25% of mouse HSC with potential for therapeutic applications.
DOI 10.1101/2022.12.15.520650