Epidermal TRPV4 ion channels regulate UVB induced sunburn by triggering inflammmasome activation and MAPK signaling
C. Moore, S. Choi, G. Moon, J. Zhang, Y. Chen, W. Liedtke
This study investigates how TRPV4 ion channels in keratinocytes mediate UVB-induced inflammation by activating inflammasomes and MAPK signaling, leading to IL-1β secretion and pain.
bioRxiv · Jan 9, 2021 · PreprintPhysiology