Cell BiologybioRxiv
Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes
A. Knyazeva, S. Li, D. Corkery…·Y. Wu
This study inhibits the IST1-CHMP1B interaction in ESCRT-III, impairing endosomal recycling and inducing unconventional LC3 lipidation at stalled endosomes.
DOI 10.1073/pnas.2317680121