ImmunologybioRxiv
Nanoscale organization of the endogenous ASC speck
I. M. Glueck, G. P. Mathias, S. Strauss…·D. C. Lamb
This study uses super-resolution microscopy to analyze the nanoscale structure of endogenous ASC specks during NLRP3 inflammasome activation, revealing a dense core with extending filaments and changes in density during formation.
DOI 10.1016/j.isci.2023.108382