Distinct components of nucleoside-modified messenger RNA vaccines cooperate to instruct efficient germinal center responses
E. Bettini, A. Chudnovskiy, G. Protti, S. Nakadakari-Higa, S. Ceglia, D. Castano, J. Chiu, H. Muramatsu, T. Mdluli, E. Abraham, Z. Lipinszki, I. Maillard, Y. Tam, A. Reboldi, N. Pardi, , M. Locci
This study identifies distinct roles of nucleoside-modified mRNA and lipid nanoparticles in promoting Tfh cell responses through different mechanisms.
bioRxiv · May 17, 2024 · PreprintImmunology