Author

I. Maillard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:flow cytometry· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1

Frequent Co-Authors

A. Vanderbeck· 2 shared E. Perkey· 2 shared J. D. Brandstadter· 2 shared L. J. Carrington· 2 shared A. Allman· 1 shared A. Crayton· 1 shared A. De Martin· 1 shared A. Ferreira· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

A. Vanderbeck

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease

J. D. Brandstadter, A. De Martin, M. Lutge, A. Ferreira, B. T. Gaudette, Y. Stanossek, S. Wang, M. V. Gonzalez, E. Camiolo, G. Wertheim, B. Austin, D. Allman, M. S. Lim, D. C. Fajgenbaum, J. C. Aster, , I. Maillard

This study demonstrates that cryopreservation of lymphoid tissue allows for the study of non-hematopoietic stromal cells in human disease, preserving cell type proportions and transcriptional profiles.

bioRxiv · Feb 6, 2023Immunology

Evolutionarily conserved effects of Notch signaling drive intestinal graft-versus-host disease in mice and non-human primates

V. Tkachev, A. Vanderbeck, E. Perkey, S. N. Furlan, C. McGuckin, D. Gomez Atria, U. Gerdemann, X. Rui, J. Lane, D. J. Hunt, H. Zheng, L. Colonna, M. Hoffman, A. Yu, S. Kelly, , I. Maillard

This study shows that Notch signaling, specifically through DLL4, promotes intestinal GVHD in mice and non-human primates by enhancing effector T-cell infiltration and reducing regulatory T-cell activity.

bioRxiv · Apr 23, 2022 · PreprintImmunology

Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline

J. V. Graniel, K. Bisht, A. Friedman, J. White, E. Perkey, A. Vanderbeck, A. Moroz, L. J. Carrington, J. D. Brandstadter, F. Allen, A. N. Shami, P. Thomas, A. Crayton, M. Manzor, A. Mychalowych, , J. Nandakumar

This study examines the impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline, finding progressive telomere erosion and infertility without bone marrow failure.

Life Science Alliance · Oct 13, 2021Peer-reviewedCell Biology

Systemic inflammation recruits fast-acting anti-inflammatory innate myeloid progenitors from BM into lymphatics

J. Serrano-Lopez, S. Hegde, S. Kumar, J. Serrano, J. Fang, A. Wellendorf, P. Roche, Y. Rangel, L. J. Carrington, H. Geiger, L. Grimes, S. Luther, I. Maillard, J. Sanchez-Garcia, D. Starczynowski, J. Cancelas

The paper shows that systemic inflammation triggers rapid migration of specific myeloid progenitors from bone marrow to lymphatics via Ccl19/Ccr7, promoting anti-inflammatory responses and replenishment of lymph node dendritic cells.

bioRxiv · Jan 20, 2021 · PreprintImmunology