Author

A. Reboldi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 6 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

F. Raso· 3 shared S. Ceglia· 3 shared A. Berthelette· 2 shared K. Howley· 2 shared A. Cerutti· 1 shared A. D. Polydorides· 1 shared A. Dunn· 1 shared A. Krek· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersImmunology

F. Raso

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine

T. D. Kellogg, S. Ceglia, B. M. Mortzfeld, A. L. Zeamer, S. E. Foley, D. Ward, S. K. Bhattarai, B. A. McCormick, A. Reboldi, V. Bucci

This study shows that succinate from the microbiota expands tuft cells in the colon, enhancing type 2 immunity and reducing C. difficile-induced disease.

bioRxiv · Jan 29, 2024 · PreprintImmunology

Embryonic type 3 innate lymphoid cells sense maternal dietary cholesterol to control local Peyer's patch development

K. Howley, A. Berthelette, S. Ceglia, J. Kang, A. Reboldi

The paper identifies how maternal dietary cholesterol influences Peyer's patch development through LTi cell GPR183 sensing of 7,25-HC.

bioRxiv · Mar 19, 2023 · PreprintImmunology

Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation.

F. Raso, S. Liu, M. J. Willett, G. Barton, C. T. Mayer, O. Bannard, M. Acharya, J. Muppidi, A. Marshak-Rothstein, A. Reboldi

This study shows that IgA BCR signaling enhances B cell fitness and promotes diverse IgA responses to gut commensals by rescuing low-affinity B cells and redirecting plasma cell homing.

bioRxiv · Mar 16, 2023Immunology

Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis

P. Canales-Herrerias, M. Uzzan, A. Seki, R. S. Czepielewski, B. Verstockt, A. Livanos, F. Raso, A. Dunn, D. Dai, A. Wang, Z. Al-taie, J. Martin, H. M. Ko, M. Tokuyama, M. Tankelevich, , S. Mehandru

This study investigates the mechanism of vedolizumab in ulcerative colitis by analyzing immune cell changes in gut-associated lymphoid tissue and shows that targeting GALT is a novel mechanism of action.

bioRxiv · Jan 19, 2023Immunology

The Tec kinase ITK differentially optimizes NFAT, NF-κB, and MAPK signaling during early T cell activation to regulate graded gene induction

M. P. Gallagher, J. M. Conley, P. Vangala, A. Reboldi, M. Garber, L. J. Berg

This study shows ITK differentially optimizes NFAT, NF-κB, and MAPK signaling during T cell activation, leading to graded gene induction based on TCR signal strength.

bioRxiv · Nov 12, 2020Immunology

Intracellular sterol sensing controls intestinal B cell differentiation

B. C. Trindade, S. Ceglia, A. Berthelette, F. Raso, K. Howley, J. R. Muppidi, A. Reboldi

This study shows that 25-HC-SREBP2 signaling regulates intestinal B cell differentiation, promoting plasma cell formation and IgA responses.

bioRxiv · Nov 3, 2020 · PreprintImmunology