Author

J. Chiu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Organism:multiple species· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Baum· 1 shared A. Coppola· 1 shared A. Dupuy· 1 shared A. J. Lay· 1 shared A. J. Murphy· 1 shared A. Romero Hernandez· 1 shared A. T. Hooper· 1 shared A. Yeheskel· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

A. Baum

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dynamic Disulfide Bond Topologies in von-Willebrand-Factor's C4-Domain Undermine Platelet Binding

F. Kutzki, D. Butera, A. J. Lay, D. M. Maag, J. Chiu, H.-G. Woon, T. Kubar, M. Elstner, C. Aponte-Santamaria, P. Hogg, F. Graeter

This study quantifies disulfide bond topologies in vWF-C4 domain and shows their impact on platelet binding through integrin.

bioRxiv · Aug 20, 2022 · PreprintBiophysics

Mechano-redox control of Mac-1 de-adhesion from ICAM-1 by protein disulfide isomerase promotes directional movement of neutrophils under flow

A. Dupuy, C. Aponte Santamaria, A. Yeheskel, F. Gräter, P. J. Hogg, F. H. Passam, J. Chiu

This study identifies PDI-mediated cleavage of a disulfide bond in Mac-1 as a mechanism enabling neutrophil directional movement under flow by promoting de-adhesion from ICAM-1.

bioRxiv · Mar 29, 2022Biochemistry

REGEN-COV protects against viral escape in preclinical and human studies

R. Copin, A. Baum, E. Wloga, K. E. Pascal, S. Giordano, B. O. Fulton, A. Zhou, N. Negron, K. Lanza, N. Chan, A. Coppola, J. Chiu, M. Ni, G. S. Atwal, A. Romero Hernandez, , C. A. Kyratsous

This study shows that REGEN-COV, a combination of non-competing antibodies, provides broad coverage against SARS-CoV-2 variants and prevents the emergence of new variants in clinical and preclinical settings.

bioRxiv · Mar 10, 2021 · PreprintMicrobiology