Author

J. Sherman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 2 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Research Focus:ecology & biodiversity· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

E. Meijaard· 3 shared M. Ancrenaz· 2 shared M. j. Struebig· 2 shared M. Voigt· 2 shared S. A. Wich· 2 shared T. Santika· 2 shared A. Kasumova· 1 shared A. Rodriguez· 1 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersEcology

E. Meijaard

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Mitochondrial Dysfunction is a Driver for SP-2509 Drug Resistance in Ewing Sarcoma

E. J. P. Tokarsky, J. C. Crow, L. M. Guenther, J. Sherman, C. Taslim, G. Alexe, K. I. Pishas, G. Rask, B. S. Justis, A. Kasumova, K. Stegmaier, S. L. Lessnick, E. R. Theisen

The paper identifies mitochondrial dysfunction as a mechanism of resistance to the LSD1 inhibitor SP-2509 in Ewing sarcoma and suggests combining LSD1 inhibitors with mitochondrial-targeting agents.

bioRxiv · Dec 13, 2021Cancer Biology

Deforestation projections imply range-wide population decline for critically endangered Bornean orangutan

M. Voigt, H. S. Kühl, M. Ancrenaz, D. Gaveau, E. Meijaard, T. Santika, J. Sherman, S. A. Wich, F. Wolf, M. j. Struebig, H. M. Pereira, I. M. Rosa

The paper projects deforestation impacts on Bornean orangutan populations, finding significant habitat loss in unprotected forests and oil palm concessions by 2030.

bioRxiv · Jul 16, 2021Ecology

Mapping Protein Numbers in Living Cells

D. J. Thirstrup, J. Yao, J. Sherman, I. A. Mueller, W. Wiegraebe

The paper introduces a method to quantify protein numbers in live cells using fluorescence imaging and calibration curves, enabling 3D maps of protein density.

bioRxiv · Jul 2, 2021 · PreprintCell Biology

Artemisinin-based hybrids produce intracellular proteasome inhibitors that overcome resistance in Plasmodium falciparum

W. Zhan, Y. J. Liu, C. Yang, H. Zhang, J. C. Harris, R. Wang, S. Zhu, J. Sherman, G. Sukenick, A. Rodriguez, H. Deng, C. F. Nathan, L. A. Kirkman, G. Lin

This study designs artezomibs, artemisinin-proteasome inhibitor hybrids, which overcome resistance in Plasmodium falciparum by targeting proteasomes, including those with mutations.

bioRxiv · Jun 21, 2021 · PreprintMicrobiology

The historic range and drivers of decline of the Tapanuli orangutan

E. Meijaard, S. Ni'matullah, R. Dennis, J. Sherman, O. Onrizal, S. A. Wich

This study reconstructs the historical range and decline drivers of the Tapanuli orangutan, showing habitat fragmentation and hunting led to population loss before industrial deforestation.

bioRxiv · Aug 11, 2020Zoology

The importance of orangutans in small fragments for maintaining metapopulation dynamics

M. Ancrenaz, F. Oram, N. Nardiyono, M. Silmi, M. E. M. Jopony, M. Voigt, D. J. I. Seaman, J. Sherman, I. Lackman, C. Traeholt, S. Wich, M. J. Struebig, T. Santika, E. Meijaard

This paper shows that orangutans can survive in small forest fragments within human-modified landscapes, maintaining metapopulation connectivity and gene flow, challenging the need for routine translocations.

bioRxiv · May 17, 2020 · PreprintEcology