Author

G. Saffi

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

C. H. Choy· 1 shared C. Wallace· 1 shared G. Lenk· 1 shared M. A. Gray· 1 shared R. J. Botelho· 1 shared R. M. Dayam· 1 shared R. Puertollano· 1 shared S. C. Watkins· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

C. H. Choy

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1 paper

Recent·Most cited

Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence

C. H. Choy, G. Saffi, M. A. Gray, C. Wallace, R. M. Dayam, Z.-Y. A. Ou, G. Lenk, R. Puertollano, S. C. Watkins, R. J. Botelho

This study shows that PIKfyve inhibition causes lysosome coalescence, leading to fewer enlarged lysosomes, and that TFEB-mediated biosynthesis does not drive this swelling.

bioRxiv · Apr 5, 2018Cell Biology