Author

C. H. Choy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

R. J. Botelho· 2 shared C. Wallace· 1 shared E. Ospina-Escobar· 1 shared G. Lenk· 1 shared G. Saffi· 1 shared J. B. McPhee· 1 shared M. A. Gray· 1 shared N. Porco· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

R. J. Botelho

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2 papers

Recent·Most cited

Cell BiologyMicrobiology SpectrumPeer-reviewedJan 11, 2024

Salmonella actively modulates TFEB in murine macrophages in a growth-phase and time-dependent manner

S. Inpanathan, E. Ospina-Escobar, V. C. Li…·R. J. Botelho

This study shows Salmonella modulates TFEB in macrophages depending on its growth phase and infection time, with stationary-phase Salmonella delaying TFEB nuclear mobilization while late-log Salmonella allows TFEB activation.

DOI 10.1128/spectrum.04981-22

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivApr 5, 2018

Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence

C. H. Choy, G. Saffi, M. A. Gray…·R. J. Botelho

This study shows that PIKfyve inhibition causes lysosome coalescence, leading to fewer enlarged lysosomes, and that TFEB-mediated biosynthesis does not drive this swelling.

DOI 10.1242/jcs.213587

mousebulk RNA-seq

𝕏 PostBluesky