Cancer BiologybioRxiv
Increased glucose availability sensitizes pancreatic cancer to chemotherapy
A. Vaziri-Gohar, J. J. Hue, H. J. Graor…·J. M. Winter
This study shows that high glucose levels increase the effectiveness of chemotherapy in pancreatic cancer by reducing glutathione biosynthesis, which enhances oxidative stress in cancer cells.
DOI 10.1038/s41467-023-38921-8