Inferring the mode and strength of ongoing selection
The paper introduces TIDES, a method for inferring natural selection in single generations using family trio data, without assuming demography or linkage.
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The paper introduces TIDES, a method for inferring natural selection in single generations using family trio data, without assuming demography or linkage.
The paper develops a statistical method to jointly infer genealogies, recombination rates, and mutation rates in Drosophila melanogaster, finding that mutation rate variation is the major driver of genome-wide diversity.
G. V. Barroso, N. Puzovic, J. Y. Dutheil
The paper analyzes transcriptional noise in mouse genes using single-cell transcriptomics data to show that pathway position, not just gene properties, drives evolutionary selection on noise levels.