Cancer BiologybioRxiv
Tissue-resident NK cells support survival in pancreatic cancer through promotion of cDC1-CD8T activity
S. Go, C. Demetriou, G. Valenzano…·E. O'Neill
The paper shows that ionizing radiation enhances immunotherapy in pancreatic cancer by increasing tissue-resident NK cells that support CD8 T cell activity through cDC1-dependent mechanisms.