Author

G. Widmalm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

A. Ruda· 3 shared J. S. Rush· 3 shared K. V. Korotkov· 3 shared N. Korotkova· 3 shared A. J. Morris· 2 shared C. W. Kenner· 2 shared G. Lambeau· 2 shared P. Deng· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMicrobiology

A. Ruda

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Author profile →

4 papers

Recent·Most cited

Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide

J. S. Rush, S. Zamakhaeva, N. R. Murner, P. Deng, A. J. Morris, C. W. Kenner, I. Black, C. Heiss, P. Azadi, K. V. Korotkov, G. Widmalm, N. Korotkova

This study identifies the structure and biosynthesis mechanism of Streptococcus mutans cell wall polysaccharide, revealing key modifications and their roles in bacterial morphology and biofilm formation.

bioRxiv · May 9, 2024 · PreprintMicrobiology

A platform for the recombinant production of Group A Streptococcus glycoconjugate vaccines

S. Ajay Castro, I. J. Passmore, D. Ndeh, H. A. Shaw, A. Ruda, K. Burns, S. Thomson, R. Nagar, K. Alagesan, K. Lucas, S. Abouelhadid, M. Reglinski, U. Schwarz- Linek, F. Mawas, G. Widmalm, , H. C. Dorfmueller

This study develops a platform for recombinant production of Group A Streptococcus glycoconjugate vaccines using E. coli, confirming their structural integrity and immunogenicity in animal models.

bioRxiv · Mar 1, 2024Microbiology

PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides

J. S. Rush, P. Parajuli, A. Ruda, J. Li, A. A. Pohane, S. Zamakhaeva, M. M. Rahman, J. C. Chang, A. Gogos, C. W. Kenner, G. Lambeau, M. J. Federle, K. V. Korotkov, G. Widmalm, N. Korotkova

This study identifies PplD as a de-N-acetylase that modifies the cell wall linkage unit of streptococcal rhamnopolysaccharides, enhancing resistance to host antimicrobial proteins.

bioRxiv · Sep 23, 2021Microbiology

Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

R. J. Edgar, V. P. van Hensbergen, A. Ruda, A. G. Turner, P. Deng, Y. Le Breton, N. M. El-Sayed, A. T. Belew, K. S. McIver, A. G. McEwan, A. J. Morris, G. Lambeau, M. J. Walker, J. S. Rush, K. V. Korotkov, , N. Korotkova

The paper identifies a glycerol phosphate modification on streptococcal rhamnose polysaccharides, revealing its role in host-pathogen interactions and vaccine design.

bioRxiv · Jan 27, 2019Microbiology