Author

S. Thomson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

H. C. Dorfmueller· 2 shared M. Reglinski· 2 shared S. Ajay Castro· 2 shared A. Barakat· 1 shared A. I. Lamond· 1 shared A. J. Brenes-Murillo· 1 shared A. J. Howden· 1 shared A. N. Macintyre· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

H. C. Dorfmueller

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A platform for the recombinant production of Group A Streptococcus glycoconjugate vaccines

S. Ajay Castro, I. J. Passmore, D. Ndeh, H. A. Shaw, A. Ruda, K. Burns, S. Thomson, R. Nagar, K. Alagesan, K. Lucas, S. Abouelhadid, M. Reglinski, U. Schwarz- Linek, F. Mawas, G. Widmalm, , H. C. Dorfmueller

This study develops a platform for recombinant production of Group A Streptococcus glycoconjugate vaccines using E. coli, confirming their structural integrity and immunogenicity in animal models.

bioRxiv · Mar 1, 2024Microbiology

What Does Large-scale Electrodermal Sensing Reveal?

D. McDuff, S. Thomson, S. Abdel-Ghaffar, I. Galatzer-Levy, M.-Z. Poh, J. Sunshine, A. Barakat, C. Heneghan, L. Sunden

This study evaluates large-scale electrodermal sensing using Fitbit Sense 2 devices to analyze physiological responses to stressors and circadian rhythms across 16,000 individuals.

bioRxiv · Feb 22, 2024 · PreprintPhysiology

Recombinant Group A Carbohydrate backbone embedded into Outer Membrane Vesicles is a potent vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

S. Ajay Castro, S. Thomson, A. Zorzoli, B. H. Meyer, M. Reglinski, H. C. Dorfmueller

This study demonstrates that recombinant polyrhamnose (pRha) embedded in outer membrane vesicles (OMVs) induces potent antibodies against Group A Streptococcus, effectively killing hypervirulent strains.

bioRxiv · Nov 12, 2021 · PreprintMicrobiology

Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection

A. S. Chawla, M. Vandereyken, M. Arias, L. Santiago, D. Dikovskaya, C. Nguyen, N. Skariah, N. Wenner, N. Golovchenko, S. Thomson, E. Ondari, M. Garzon-Tituana, C. J. Anderson, M. Bergkessel, J. C. D. Hinton, , M. Swamy

This study shows that granzymes A and B use distinct cell death pathways to protect against intestinal Salmonella infection by balancing bacterial growth and translocation.

bioRxiv · Nov 7, 2021Immunology

A membrane-depolarising toxin substrate of the Staphylococcus aureus Type VII secretion system mediates intra-species competition

F. R. Ulhuq, M. C. Gomes, G. Duggan, M. Guo, C. Mendonca, G. Buchanan, J. D. Chalmers, Z. Cao, H. Kneuper, S. Murdoch, S. Thomson, H. Strahl, M. Trost, S. Mostowy, T. Palmer

This paper identifies TspA as a new T7SS substrate in S. aureus, showing it mediates intra-species competition by membrane depolarization and growth inhibition in vivo.

bioRxiv · Jun 2, 2020 · PreprintMicrobiology

Antigen receptor control of methionine metabolism in T cells

L. V. Sinclair, A. J. Howden, A. J. Brenes-Murillo, L. Spinelli, J. L. Hukelmann, A. N. Macintyre, X. Liu, S. Thomson, P. M. Taylor, J. C. Rathmell, J. W. Locasale, A. I. Lamond, D. A. Cantrell

This study shows antigen receptor engagement controls methionine cycle flux and methyl donor availability for RNA and histone methylation in T cells.

bioRxiv · Dec 18, 2018Immunology