Pharmacology & ToxicologybioRxiv
A molecular lid mechanism of K+ channelblocker action revealed by a cone peptide
C. Saikia, O. Dym, H. Altman-Gueta…·I. Karbat
The paper investigates two cone peptides' mechanisms of blocking K+ channels in Drosophila Shaker, revealing a 'molecular lid' mechanism for one peptide.
DOI 10.1016/j.jmb.2021.166957