PathologybioRxivPreprint
Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression
M. Carossino, P. Montanaro, A. O'Connell…·N. Crossland
This study investigates SARS-CoV-2 infection in K18-hACE2 mice, showing neuroinvasion and neuronal injury are key to lethality, with viral tropism not fully dependent on hACE2 expression.
DOI 10.1101/2021.01.13.425144