Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
J. Joseph, H. M. Baby, J. R. Quintero, D. Kenney, Y. Mebratu, E. Bhatia, P. Shah, K. Swain, S. Kaur, X. L. Li, J. Mwangi, O. Snapper, R. Nair, E. Agus, S. Ranganathan, , N. Joshi
This paper introduces a drug-free nasal spray that captures and neutralizes respiratory pathogens, showing high efficacy in mice against influenza.
bioRxiv · Oct 2, 2023 · PreprintBioengineering
J. E. McGee, J. R. Kirsch, D. Kenney, E. Chavez, T.-Y. Shih, F. Douam, W. W. Wong, M. W. Grinstaff
This paper shows that complete substitution of nucleotides in self-amplifying RNA (saRNA) reduces interferon response and enhances expression, improving vaccine potency.
bioRxiv · Sep 15, 2023Bioengineering
D.-Y. Chen, D. Kenney, C.-V. Chin, A. H. Tavares, N. Khan, H. L. Conway, G. Liu, M. C. Choudhary, H. P. Gertje, A. K. O'Connell, D. N. Kotton, A. Herrmann, A. Ensser, J. H. Connor, M. Bosmann, , M. Saeed
This study compares the pathogenicity and immune evasion of an Omicron S-bearing virus with natural Omicron, showing vaccine escape via S mutations but severe disease due to factors outside S.
bioRxiv · Oct 13, 2022 · PreprintMicrobiology
S. Ghosh, C. Villacorta-Martin, J. Lindstrom-Vautrin, D. Kenney, C. S. Golden, C. V. Edwards, V. Sanchorawala, L. H. Connors, R. M. Giadone, G. J. Murphy
The paper exposes cells to destabilized TTR variants and analyzes transcriptional and epigenetic responses to identify cell- and protein-specific signatures of amyloidogenic stress.
bioRxiv · Aug 17, 2022Cell Biology
S. Subramaniam, R. M. Hekman, A. Jayaraman, A. K. O'Connell, P. Montanaro, B. Blum, D. Kenney, M. Ericsson, K. Ravid, N. A Crossland, A. Emili, F. Douam, M. Bosmann
This paper uses proteomics to analyze platelet changes in SARS-CoV-2-infected humanized mice, finding early activation of coagulation and complement pathways.
bioRxiv · Aug 19, 2021 · PreprintImmunology
M. Carossino, P. Montanaro, A. O'Connell, D. Kenney, H. Gertje, K. Grosz, M. Ericsson, B. R. Huber, S. Subramaniam, T. A. Kirkland, J. R. Walker, K. P. Francis, A. D. Klose, N. Paragas, S. Kurnick, , N. Crossland
This study investigates SARS-CoV-2 infection in K18-hACE2 mice, showing neuroinvasion and neuronal injury are key to lethality, with viral tropism not fully dependent on hACE2 expression.
bioRxiv · Jan 13, 2021 · PreprintPathology
D. W. Sanders, C. C. Jumper, P. J. Ackerman, D. Bracha, A. Donlic, H. Kim, D. Kenney, I. Castello-Serrano, S. Suzuki, T. Tamura, A. H. Tavares, M. Saeed, A. S. Holehouse, A. Ploss, I. Levental, , C. P. Brangwynne
This study identifies cholesterol's essential role in SARS-CoV-2 membrane fusion and syncytia formation, suggesting statins may benefit COVID-19 patients.
bioRxiv · Dec 14, 2020Cell Biology
D.-Y. Chen, N. Khan, B. J. Close, R. K. Goel, B. Blum, A. H. Tavares, D. Kenney, H. L. Conway, J. K. Ewoldt, S. Kapell, V. C. Chitalia, N. A. Crossland, C. S. Chen, D. N. Kotton, S. C. Baker, , M. Saeed
This study identifies SARS-CoV-2 inhibition of the JAK-STAT pathway as a mechanism to suppress interferon signaling across diverse cell types.
bioRxiv · Oct 27, 2020 · PreprintMicrobiology