H. H. Yang

The paper analyzes melanoma clonal sublines to uncover how intratumoral heterogeneity drives resistance to immunotherapy.

This study generates human chambered cardiac organoids from pluripotent stem cells to model cardiac hypertrophy and improve cardiovascular disease research.

This study compares metastasis-specific gene expression in different mouse breast cancer models and identifies clinically targetable pathways involved in metastatic spread.

The paper develops a preclinical platform using syngeneic mouse models to predict melanoma patient response to immunotherapy and identifies a melanocytic plasticity signature linked to treatment outcomes.

The paper analyzes the melanoblast transcriptome to identify genes involved in melanoma metastasis and discovers a 43-gene signature predictive of patient survival.

This study identifies Rnaseh2c as a metastasis susceptibility gene in breast cancer, independent of its enzymatic activity, and links it to T cell-mediated immune responses.