Author

H. Haim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

C. Han· 3 shared A. R. Rojas Chavez· 2 shared D. Boyt· 2 shared K. J. Rogers· 2 shared N. Ruggio· 2 shared W. Maury· 2 shared A. E. Merrill· 1 shared A. J. Kort· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMicrobiology

C. Han

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Limited variation between SARS-CoV-2-infected individuals in domain specificity and relative potency of the antibody response against the spike glycoprotein

H. A. Van Ert, D. W. Bohan, K. J. Rogers, M. Fili, A. R. Rojas Chavez, E. Qing, C. Han, S. M. Dempewolf, G. Hu, N. Schwery, K. M. Sevcik, N. Ruggio, D. Boyt, M. Pentella, T. Gallagher, , H. Haim

The paper analyzes antibody responses in SARS-CoV-2-infected individuals, finding limited variation in domain specificity and relative neutralization potency across subjects.

bioRxiv · Aug 4, 2021Microbiology

Phosphatidylserine Receptors Enhance SARS-CoV-2 Infection: AXL as a Therapeutic Target for COVID-19

D. Bohan, H. Van Ert, N. Ruggio, K. J. Rogers, M. Baddredine, J. A. A. Briseno, R. A. Rojas Chavez, B. Gao, T. Stokowy, E. Christakou, D. Micklem, G. Gausdal, H. Haim, J. Minna, J. B. Lorens, W. Maury

This study identifies PS receptors, including AXL, as facilitators of SARS-CoV-2 infection by enhancing virus entry into human lung cells, suggesting AXL as a therapeutic target for COVID-19.

bioRxiv · Jun 15, 2021Microbiology

The fusion peptide proximal region of the HIV-1 envelope glycoproteins regulates exposure of immunogenic epitopes at the trimer base

A. R. Rojas Chavez, D. Boyt, C. Han, L. Wu, H. Haim

The paper examines how alanine substitutions in the HIV-1 Env FPPR region affect trimer conformation and epitope exposure, revealing weak antibody pressures shaping Env evolution.

bioRxiv · Oct 28, 2020Microbiology

Gradual decrease in the inter-population diversity of HIV-1 Env among group M lineages worldwide

C. Han, J. M. Johnson, R. Dong, R. Kandula, A. J. Kort, M. Wong, T. Yang, P. J. Breheny, G. D. Brown, H. Haim

The paper analyzes the evolution of HIV-1 Env diversity across clades and regions, finding that inter-population diversity decreases while intra-population diversity increases due to conserved selective pressures.

bioRxiv · Sep 4, 2019 · PreprintEvolutionary Biology