Author

H. Ingmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 10

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Organism:human· 6 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. S. Bojer· 4 shared B. S. Bejder· 3 shared J. Z. Bowring· 3 shared B. H. Gless· 2 shared C. A. Olsen· 2 shared K. Mikkelsen· 2 shared M. Vestergaard· 2 shared P. S. Andersen· 2 shared

Activity by Year

2019-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersMicrobiology

M. S. Bojer

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10 papers

Recent·Most cited

A short-lived peptide signal regulates cell-to-cell communication in Listeria monocytogenes

B. S. Bejder, F. Monda, B. H. Gless, M. S. Bojer, H. Ingmer, C. A. Olsen

The paper develops stabilized AIP analogues to study QS in L. monocytogenes, finding that the short-lived thiolactone-containing pentamer is the most potent AIP.

bioRxiv · Jul 4, 2023 · PreprintMicrobiology

Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus

J. Yang, J. Z. Bowring, J. Krusche, B. S. Bejder, S. F. Silva, M. S. Bojer, T. Grunert, A. Peschel, H. Ingmer

The paper shows that quorum sensing in Staphylococcus aureus controls phage susceptibility by modulating receptor structures, and that cross-species communication with non-aureus staphylococci can protect S. aureus from phage infection.

bioRxiv · Apr 3, 2023 · PreprintMicrobiology

Endogenous Staphylococcus aureus CRISPR-cas system limits phage proliferation and efficiently excises from the genome as part of the SCCmec cassette

K. Mikkelsen, J. Z. Bowring, Y. K. Ng, F. S. Frisinger, J. K. Maglegaard, Q. Li, R. N. Sieber, A. Petersen, P. S. Andersen, J. T. Rostoel, N. M. Hoeyland-Kroghsbo, H. Ingmer

This study shows that S. aureus CRISPR-Cas systems, located within SCCmec cassettes, limit phage proliferation but are inefficient, with phages able to escape or overload the system.

bioRxiv · Mar 19, 2023 · PreprintMicrobiology

Polyether ionophore antibiotics target drug-resistant clinical isolates, persister cells, and biofilms

M. Wollesen, K. Mikkelsen, M. S. Tvilum, M. Vestergaard, M. Wang, H. Ingmer, R. L. Meyer, T. B. Poulsen, T. Torring

This study compares nine polyether ionophores to identify those with promising antibiotic activity against drug-resistant clinical isolates, biofilms, and persister cells.

bioRxiv · Feb 13, 2023Microbiology

Quorum sensing inhibits Type III-A CRISPR-Cas system activity through repressing positive regulators SarA and ArcR in Staphylococcus aureus

Y. Li, X. Li, Y. Tang, N. M. Hoyland-Kroghsbo, H. Ingmer, X. Jiao, Q. Li

The paper shows quorum sensing represses the Type III-A CRISPR-Cas system in S. aureus by inhibiting SarA and ArcR, which are positive regulators of the system.

bioRxiv · Jan 17, 2023 · PreprintMicrobiology

Bacteriophages encoding human immune evasion factors adapt to livestock-associated MRSA through rounds of integration and excision

H. Leinweber, R. Sieber, J. Larsen, M. Stegger, H. Ingmer

This study shows Sa3int phages adapt to livestock-associated MRSA by mutating their attachment sequence to enhance integration at alternative sites.

bioRxiv · Apr 29, 2021 · PreprintMicrobiology

Chemical phylogenetics of the staphylococcal quorum sensing landscape

B. H. Gless, B. S. Bejder, L. Vitolo, L. Marques, P. S. Andersen, M. S. Bojer, H. Ingmer, C. A. Olsen

The paper maps staphylococcal quorum sensing interactions by testing over 200 AIPs against reporter strains, identifying a pan-inhibitory AIP that reduces MRSA skin infection in mice.

bioRxiv · Apr 18, 2021 · PreprintMicrobiology

Screening for highly transduced genes in Staphylococcus aureus reveals both lateral and specialized transduction

J. Z. Bowring, Y. Su, A. Alsaadi, S. L. Svenningsen, J. Parkhill, H. Ingmer

The paper screens a transposon mutant library in Staphylococcus aureus to identify genes enhancing transduction by phage φ11, revealing both lateral and specialized transduction mechanisms.

bioRxiv · Oct 28, 2020 · PreprintMicrobiology

Human antimicrobial peptide, LL-37, induces non-inheritable reduced susceptibility to vancomycin in Staphylococcus aureus

C. Freiberg, J. Haaber, M. Vestergaard, A. Fait, V. Perrot, B. R. Levin, H. Ingmer

This study shows that LL-37 increases vancomycin resistance in S. aureus, potentially affecting treatment outcomes in vivo.

bioRxiv · Dec 24, 2019Microbiology

SosA inhibits cell division in Staphylococcus aureus in response to DNA damage

M. S. Bojer, K. Wacnik, P. Kjelgaard, C. Gallay, A. L. Bottomley, M. T. Cohn, G. Lindahl, D. Frees, J.-W. Veening, S. J. Foster, H. Ingmer

This paper identifies SosA as a DNA-damage-inducible cell-division inhibitor in Staphylococcus aureus, showing it halts division at a specific stage and is regulated by membrane protease CtpA.

bioRxiv · Feb 22, 2019Microbiology