Author

H. J. Mortiboys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. J. Brazel· 1 shared C. A. Loynes· 1 shared C. Henriques· 1 shared H. Elcocks· 1 shared I. Bellantuono· 1 shared K. Husnjak· 1 shared K. R. McCarron· 1 shared M. J. Clague· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. J. Brazel

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Author profile →

2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 11, 2022

FBXL4 deficiency promotes mitophagy by elevating NIX.

H. Elcocks, A. J. Brazel, K. R. McCarron…·S. Urbe

This study identifies FBXL4 as a negative regulator of basal mitophagy through NIX stabilization, showing that its deficiency promotes mitophagy and suggesting MLN4924 as a potential therapeutic agent for mitochondrial diseases.

DOI 10.1101/2022.10.11.511735

humanproteomics

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivSep 19, 2022

A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo.

S. Morsli, C. Henriques, P. s. Ellis…·I. Bellantuono

This paper develops a zebrafish model expressing p21-GFP to study senescence and test senolytics, showing that quercetin and dasatinib reduce senescent cells in a 5-day assay.

DOI 10.1111/acel.13835

zebrafishfluorescence / live-cell microscopy

𝕏 PostBluesky