H. K. Hoffman

TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cells

This study identifies TTLL12 as a novel microtubule regulator required for primary ciliary axoneme formation in polarized epithelial cells.

HOPS-dependent lysosomal fusion controls Rab19 availability for ciliogenesis in polarized epithelial cells

The paper shows that HOPS-dependent lysosomal fusion is necessary for Rab19 availability at the basal body, which is critical for apical actin clearing and ciliogenesis in polarized epithelial cells.

Rab11-FIP1C is dispensable for HIV-1 replication in primary CD4+ T cells but its role is cell-type-dependent in immortalized human T-cell lines

This study shows FIP1C is not essential for HIV-1 replication in primary CD4+ T cells but has cell-type-dependent effects in T-cell lines.

An open-access volume electron microscopy atlas of whole cells and tissues

The paper presents a 3D electron microscopy atlas of whole cells and tissues with high resolution and large volume, enabling new biological insights.

Elucidating the basis for permissivity of the MT-4 T-cell line to replication of an HIV-1 mutant lacking the gp41 cytoplasmic tail

This study investigates why MT-4 T-cells allow HIV-1 replication despite lacking the gp41 cytoplasmic tail, finding faster viral production, higher surface Env, and increased cell-to-cell transmission contribute to this permissivity.

Rab14/MACF2/CAMSAP3 Complex Regulates Endosomal Targeting to the Abscission Site During Cytokinesis

This study identifies Rab14 as a regulator of abscission by facilitating Rab11-endosome targeting to the central spindle during cytokinesis.