Author

H. Hess

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:deep learning· 2 Assay:electronic health records· 2 Research Focus:database / resource· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

C. S. Xu· 2 shared D. Bennett· 2 shared J. Lippincott-Schwartz· 2 shared A. Müller· 1 shared A. Petruncio· 1 shared A. T. Ritter· 1 shared A. V. Weigel· 1 shared A. Weigel· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

C. S. Xu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Replicating enzymatic activity by positioning active sites with synthetic protein scaffolds

Y. Ding, S. Zhang, H. Hess, X. Kong, Y. Zhang

The paper demonstrates a computational strategy to design new PET hydrolases by replicating functional motifs from a template enzyme using deep learning and molecular computations, resulting in enzymes with high activity and thermostability.

bioRxiv · Jan 31, 2024 · PreprintBiochemistry

An open-access volume electron microscopy atlas of whole cells and tissues

C. S. Xu, S. Pang, G. Shtengel, A. Müller, A. T. Ritter, H. K. Hoffman, S.-y. Takemura, Z. Lu, H. A. Pasolli, N. Iyer, J. Chung, D. Bennett, A. V. Weigel, M. Freeman, S. B. van Engelenburg, , H. Hess

The paper presents a 3D electron microscopy atlas of whole cells and tissues with high resolution and large volume, enabling new biological insights.

Nature · Oct 6, 2021Peer-reviewedCell Biology

Automatic whole cell organelle segmentation in volumetric electron microscopy

L. Heinrich, D. Bennett, D. Ackerman, W. Park, J. Bogovic, N. Eckstein, A. Petruncio, J. Clements, C. S. Xu, J. Funke, W. Korff, H. Hess, J. Lippincott-Schwartz, S. Saalfeld, A. Weigel, C. Project Team

The paper develops an automatic pipeline for segmenting and analyzing organelles in whole cells using FIB-SEM data, enabling quantification of spatial interactions and cross-modality registration.

bioRxiv · Nov 14, 2020 · PreprintCell Biology